Preprints
Tang AS, Wei ML, Haemel A, La C, Sirota M, Lee EY.
Artificial intelligence-enabled precision medicine for inflammatory skin diseases.
ArXiv [Preprint]. 2025 May 14:arXiv:2505.09527v1. PMID: 40463698; PMCID: PMC12133082.
Katsuhara Y, Khan U, Miller ZA, Allen IE, Oskotsky TT, Sirota M, Tang AS.
Decoding subphenotypes in electronic medical records within late-onset Alzheimer's disease reveals heterogeneity and sex-specific differences.
medRxiv [Preprint]. 2025 Apr 25:2025.04.24.25326306. doi: 10.1101/2025.04.24.25326306. PMID: 40313288; PMCID: PMC12045436.
Breithaupt AG, Weiner M, Tang AS, Possin KL, Sirota M, Lah J, Levey AI, Hentenryck PV, Zandehshahvar R, Gorno-Tempini ML, Giorgio J, Wang J, Rauschecker AM, Rosen HJ, Nosheny RL, Miller BL, Pinheiro-Chagas P.
Integrating Generative Artificial Intelligence in ADRD: A Roadmap for Streamlining Diagnosis and Care in Neurodegenerative Diseases.
ArXiv [Preprint]. 2025 Feb 6:arXiv:2502.06842v2.
Publications
2025
Tang AS, Brooks L, Boudreau DM, Chanu P, Joshi A, Vora B, Zhu R.
Use of Real-World Claims Data to Assess the Prevalence of Concomitant Medications to Inform Drug-Drug Interaction Risk in Target Patient Populations.
Clin Pharmacol Ther. 2025 Jul;118(1):146-155. doi: 10.1002/cpt.3652. Epub 2025 Apr 1. PMID: 40170515.
Zhou M, Tang AS, Zhang H, Xu Z, Ke AMC, Su C, Huang Y, Mantyh WG, Jaffee MS, Rankin KP, DeKosky ST, Zhou J, Guo Y, Bian J, Sirota M, Wang F.
Identifying Progression Subphenotypes of Alzheimer's Disease from Large-scale Electronic Health Records with Machine Learning.
J Biomed Inform. 2025 May;165:104820. doi: 10.1016/j.jbi.2025.104820. Epub 2025 Apr 1. PMID: 40180206.
Ramey GD, Tang AS, Phongpreecha T, Yang MM, Woldemariam SR, Oskotsky TT, Montine TJ, Allen I, Miller ZA, Aghaeepour N, Capra JA, Sirota M.
Exposure to autoimmune disorders is associated with increased Alzhiemer’s Disease Risk in a Multi-site Electronic Health Record Analysis.
Cell Rep Med. 2025 Mar 18;6(3):101980. doi: 10.1016/j.xcrm.2025.101980. Epub 2025 Feb 24. PMID: 39999839.
Costello JM, Takasuka H, Roger J, Yin O, Tang AS, Oskotsky T, Sirota M, Capra JA.
Pre-conception clinical risk factors differ between spontaneous and indicated preterm birth in a densely phenotyped EHR cohort.
BMC Pregnancy Childbirth. 2025 Feb 12;25(1):149. doi: 10.1186/s12884-025-07166-2. PMID: 39939846.
2024
Tang AS, Woldemariam SR, Miramontes S, Norgeot B, Oskotsky TT, Sirota M.
Harnessing EHR data for health research.
Nat Med. 2024 Jul;30(7):1847-1855. doi: 10.1038/s41591-024-03074-8. Epub 2024 Jul 4. PMID: 38965433.
Tang AS, Rankin KP, Cerono G, Miramontes S, Mills H, Roger J, Zeng B, Nelson C, Soman K, Woldemariam S, Li Y, Lee A, Bove R, Glymour M, Aghaeepour N, Oskotsky TT, Miller Z, Allen IE, Sanders SJ, Baranzini S, Sirota M.
Leveraging electronic health records and knowledge networks for Alzheimer's disease prediction and sex-specific biological insights.
Nat Aging. 2024 Mar;4(3):379-395. doi: 10.1038/s43587-024-00573-8. Epub 2024 Feb 21. PMID: 38383858; PMCID: PMC10950787.
Golob JL, Oskotsky TT, Tang AS, Roldan A, Chung V, Ha CWY, Wong RJ, Flynn KJ, Parraga-Leo A, Wibrand C, Minot SS, Oskotsky B, Andreoletti G, Kosti I, Bletz J, Nelson A, Gao J, Wei Z, Chen G, Tang ZZ, Novielli P, Romano D, Pantaleo E, Amoroso N, Monaco A, Vacca M, De Angelis M, Bellotti R, Tangaro S, Kuntzleman A, Bigcraft I, Techtmann S, Bae D, Kim E, Jeon J, Joe S; Preterm Birth DREAM Community; Theis KR, Ng S, Lee YS, Diaz-Gimeno P, Bennett PR, MacIntyre DA, Stolovitzky G, Lynch SV, Albrecht J, Gomez-Lopez N, Romero R, Stevenson DK, Aghaeepour N, Tarca AL, Costello JC, Sirota M.
Microbiome preterm birth DREAM challenge: Crowdsourcing machine learning approaches to advance preterm birth research.
Cell Rep Med. 2024 Jan 16;5(1):101350. doi: 10.1016/j.xcrm.2023.101350. Epub 2023 Dec 21. PMID: 38134931
2022
Tang AS, Oskotsky T, Havaldar S, Mantyh WG, Bicak M, Solsberg CW, Woldemariam S, Zeng B, Hu Z, Oskotsky B, Dubal D, Allen IE, Glicksberg BS, Sirota M.
Deep phenotyping of Alzheimer's disease leveraging electronic medical records identifies sex-specific clinical associations.
Nat Commun. 2022 Feb 3;13(1):675. doi: 10.1038/s41467-022-28273-0. PMID: 35115528; PMCID: PMC8814236.
2020
Hu Z, Tang A, Singh J, Bhattacharya S, Butte AJ.
A robust and interpretable end-to-end deep learning model for cytometry data.
Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21373-21380. doi: 10.1073/pnas.2003026117. Epub 2020 Aug 14. PMID: 32801215; PMCID: PMC7474669.
2016
Tang A, Scalzo F.
Similarity Metric Learning for 2D to 3D Registration of Brain Vasculature.
Adv Vis Comput. 2016 Dec;10072:3-12. doi: 10.1007/978-3-319-50835-1_1. Epub 2016 Dec 10. PMID: 30656290; PMCID: PMC6333089.